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The Siuslaw River (pronounced /sa??ju?sl??/ sigh YOU slaw) is a river, approximately 110 mi (177 km) long, along the Pacific coast of Oregon in the United States. It drains an area of approximately 4560 sq mi (11900 kmĀ²) in the Central Oregon Coast Range southwest of the Willamette Valley and north of the watershed of the Umpqua River.